The impact of in-season national team soccer play on injury and player availability in a professional club

This study investigated the impact of in-season national team duty on injury rates and player availability in a professional soccer club. Time-loss injuries and exposure time during club and national team duties were recorded prospectively over 5 seasons (2009–2014). A time-loss injury was sustained by 37.7% of squad members participating in national duty, all injuries occurring in match-play. The incidence (per 1000 h exposure) for national team player match-play injuries did not differ (P = 0.608) to that for all players in club competitions: 48.0 (95% CI 20.9–75.5) vs. 41.9 (95% CI 36.5–47.4), incidence rate ratio = 1.2 (CI: 0.8–2.4). The majority (58%) of national team injuries resulted in a layoff ≤1 week. Of all working days lost to injury generally, 5.2% were lost through injury on national duty. Injury incidence in the week following national duty was comparable (P = 0.818) in players participating or not: 7.8 (95% CI 3.6–12.0) vs. 7.1 (95% CI: 4.6–9.6), incidence rate ratio = 1.1 (CI: 0.7–2.7). While approximately 40% of participating players incurred a time-loss injury on national duty, no training injuries were sustained and injuries made up a negligible part of overall club working days lost to injury. Following duty, players had a similar injury risk to peers without national obligations

Five year outcomes in a cohort study of physicians treated for substance use disorders in the United States

Objective To evaluate the effectiveness of US state physician health programmes in treating physicians with substance use disorders

Analysis of repeated high-intensity running performance in professional soccer

The aims of this study conducted in a professional soccer team were two-fold: to characterise repeated high-intensity movement activity profiles in official match-play; b) to inform and verify the construct validity of tests commonly used to determine repeated-sprint ability in soccer by investigating the relationship between the results from a test of repeated-sprint ability and repeated high-intensity performance in competition. High-intensity running performance (movement at velocities >19.8 km/h for a minimum of 1-s duration) in 20 players was measured using computerised time motion analysis. Performance in 80 French League 1 matches was analysed. In addition, 12 out of the 20 players performed a repeated-sprint test on a non-motorized treadmill consisting of 6 consecutive 6s sprints separated by 20s passive recovery intervals. In all players, the majority of consecutive high-intensity actions in competition were performed after recovery durations ≥61s, recovery activity separating these efforts was generally active in nature with the major part of this spent walking, and players performed 1.1±1.1 repeated high-intensity bouts (a minimum of 3 consecutive high-intensity with a mean recovery time ≤20s separating efforts) per game. Players reporting lowest performance decrements in the repeated-sprint ability test performed more high-intensity actions interspersed by short recovery times (≤20s, p<0.01 and ≤30s, p<0.05) compared to those with higher decrements. Across positional roles, central-midfielders performed a greater number of high-intensity actions separated by short recovery times (≤20s) and spent a larger proportion of time running at higher intensities during recovery periods while fullbacks performed the most repeated high-intensity bouts (statistical differences across positional roles from p<0.05 to p<0.001). These findings have implications for repeated high-intensity testing and physical conditioning regimens

Genomic characterization of the evolutionary potential of the sea urchin Strongylocentrotus droebachiensis facing ocean acidification

Ocean acidification (OA) is increasing due to anthropogenic CO2 emissions and poses a threat to marine species and communities worldwide. To better project the effects of acidification on organisms’ health and persistence, an understanding is needed of the 1) mechanisms underlying developmental and physiological tolerance and 2) potential populations have for rapid evolutionary adaptation. This is especially challenging in nonmodel species where targeted assays of metabolism and stress physiology may not be available or economical for large-scale assessments of genetic constraints. We used mRNA sequencing and a quantitative genetics breeding design to study mechanisms underlying genetic variability and tolerance to decreased seawater pH (-0.4 pH units) in larvae of the sea urchin Strongylocentrotus droebachiensis. We used a gene ontology-based approach to integrate expression profiles into indirect measures of cellular and biochemical traits underlying variation in larval performance (i.e., growth rates). Molecular responses to OA were complex, involving changes to several functions such as growth rates, cell division, metabolism, and immune activities. Surprisingly, the magnitude of pH effects on molecular traits tended to be small relative to variation attributable to segregating functional genetic variation in this species. We discuss how the application of transcriptomics and quantitative genetics approaches across diverse species can enrich our understanding of the biological impacts of climate change

Injury risk factors, screening tests and preventative strategies: A systematic review of the evidence that underpins the perceptions and practices of 44 football (soccer) teams from various premier leagues

Purpose: To systematically review the scientific level of evidence for the ‘Top 3’ risk factors, screening tests and preventative exercises identified by a previously published survey of 44 premier league football (soccer) teams. Also, to provide an overall scientific level of evidence and graded recommendation based on the current research literature. Methods: A systematic literature search (Pubmed [MEDLINE], SportDiscus, PEDRO and Cochrane databases). The quality of the articles was assessed and a level of evidence (1++ to 4) was assigned. Level 1++ corresponded to the highest level of evidence available and 4, the lowest. A graded recommendation (A: strong, B: moderate, C: weak, D: insufficient evidence to assign a specific recommendation) for use in the practical setting was given. Results: Fourteen studies were analysed. The overall level of evidence for the risk factors previous injury, fatigue and muscle imbalance were 2++, 4 and ‘inconclusive’, respectively. The graded recommendation for functional movement screen, psychological questionnaire and isokinetic muscle testing were all ‘D’. Hamstring eccentric had a weak graded ‘C’ recommendation, and eccentric exercise for other body parts was ‘D’. Balance/proprioception exercise to reduce ankle and knee sprain injury was assigned a graded recommendation ‘D’. Conclusions: The majority of perceptions and practices of premier league teams have a low level of evidence and low graded recommendation. This does not imply that these perceptions and practices are not important or not valid, as it may simply be that they are yet to be sufficiently validated or refuted by research

The impact of short periods of match congestion on injury risk and patterns in an elite football club

Background: The effect of fixture congestion on injury rates and patterns has received scarce attention in elite football and existing investigations have not accounted for player rotation or examined the temporal distribution and potential cause of injuries. Aim: To prospectively investigate the epidemiology of injury during short periods of fixture congestion in a professional football club. Methods: Over a 6-season period, exposure time and injury data were compared in the same players (n=25 [14 individuals]) when participating in two frequently occurring short congested fixture cycles in comparison to match-play outside these cycles. 1) two successive matches separated by an interval totalling ≤3days calculated immediately from the end of play in match 1 to the beginning of play in match 2; 2) three successive matches separated by ≤4-day intervals commencing the day immediately after each match. Results: In 2-match congestion cycles, incidence rate ratios (IRR) showed there was a higher risk of injury in the final 15-minutes of play in the second match in comparison to match-play outside the cycles (IRR: 3.1 [95% CI 1.1 to 9.3], p=0.0400). A greater risk of injury overall (IRR: 2.0 [95% CI 1.1 to 3.8], p=0.0345) and in the 1st-half of play (2.6 [1.1 to 6,5], p=0.0386), and risk of ankle sprains (10.4 [95% CI 1.9 to 57.9], p=0.0068) and non-contact injuries due to a ‘change in direction’ (IRR: 7.8 [1.3 to 46.8], p=0.0243) was observed in the final match of 3-match congestion cycles in comparison to match-play outside the cycles. Conclusion: Injury rates and patterns were affected in the same elite football players when competing in short congested fixture cycles in comparison to match-play outside the cycles

Injury prevention strategies at the FIFA 2014 World Cup: perceptions and practices of the physicians from the 32 participating national teams

Purpose The available scientific research regarding injury prevention practices in international football is sparse. The purpose of this study was to quantify current practice with regard to (1) injury prevention of top-level footballers competing in an international tournament, and (2) determine the main challenges and issues faced by practitioners in these national teams. Methods A survey was administered to physicians of the 32 competing national teams at the FIFA 2014 World Cup. The survey included 4 sections regarding perceptions and practices concerning non-contact injuries: (1) risk factors, (2) screening tests and monitoring tools, (3) preventative strategies and (4) reflection on their experience at the World Cup. Results Following responses from all teams (100%), the present study revealed the most important intrinsic (previous injury, accumulated fatigue, agonist:antagonist muscle imbalance) and extrinsic (reduced recovery time, training load prior to and during World Cup, congested fixtures) risk factors during the FIFA 2014 World Cup. The 5 most commonly used tests for risk factors were: flexibility, fitness, joint mobility, balance and strength; monitoring tools commonly used were: medical screen, minutes/matches played, subjective and objective wellness, heart rate and biochemical markers. The 5 most important preventative exercises were: flexibility, core, combined contractions, balance and eccentric. Conclusions The present study showed that many of the National football (soccer) teams’ injury prevention perceptions and practices follow a coherent approach. There remains, however, a lack of consistent research findings to support some of these perceptions and practices

A general method for manipulating DNA sequences from any organism with optical tweezers

Mechanical manipulation of single DNA molecules can provide novel information about DNA properties and protein–DNA interactions. Here we describe and characterize a useful method for manipulating desired DNA sequences from any organism with optical tweezers. Molecules are produced from either genomic or cloned DNA by PCR using labeled primers and are tethered between two optically trapped microspheres. We demonstrate that human, insect, plant, bacterial and viral sequences ranging from ∼10 to 40 kilobasepairs can be manipulated. Force-extension measurements show that these constructs exhibit uniform elastic properties in accord with the expected contour lengths for the targeted sequences. Detailed protocols for preparing and manipulating these molecules are presented, and tethering efficiency is characterized as a function of DNA concentration, ionic strength and pH. Attachment strength is characterized by measuring the unbinding time as a function of applied force. An alternative stronger attachment method using an amino–carboxyl linkage, which allows for reliable DNA overstretching, is also described

Can off-field ‘brains’ provide a competitive advantage in professional football?

‘Working-fast and working-slow’ in sport describes the concept that practice and research can be integrated to improve high-performance outcomes and enhance professional practice.1 ‘Working-fast’ is the task of the fast-thinking, intuitive practitioner operating on ‘the ground’ at a frenetic pace, interacting with coaches and athletes, and delivering the daily preparation programme. ‘Working-slow’ is key for the team's deliberate, focused researcher acting as the resident sceptic, operating behind the scenes on tasks that the ‘fast-practitioner’ may not have time and/or skills to undertake. Such hidden, but important, tasks include determining measurement noise/error in performance tests, establishing proof of concept for new ideas and ensuring validity of methods. Embedding research into the fast environment of high-performance football may provide a competitive advantage using ethical and evidence-based methods.

Improving the simulation of landfast ice by combining tensile strength and a parameterization for grounded ridges

ABSTRACT: In some coastal regions of the Arctic Ocean, grounded ice ridges contribute to stabilizing andmaintaining a landfast ice cover. Recently, a grounding scheme representing this effect on sea ice dynamicswas introduced and tested in a viscous-plastic sea ice model. This grounding scheme, based on a basalstress parameterization, improves the simulation of landfast ice in many regions such as in the East SiberianSea, the Laptev Sea, and along the coast of Alaska. Nevertheless, in some regions like the Kara Sea, the areaof landfast ice is systematically underestimated. This indicates that another mechanism such as ice archingis at play for maintaining the ice cover fast. To address this problem, the combination of the basal stressparameterization and tensile strength is investigated using a 0.258Pan-Arctic CICE-NEMO configuration.Both uniaxial and isotropic tensile strengths notably improve the simulation of landfast ice in the Kara Seabut also in the Laptev Sea. However, the simulated landfast ice season for the Kara Sea is too short com-pared to observations. This is especially obvious for the onset of the landfast ice season which systematical-ly occurs later in the model and with a slower build up. This suggests that improvements to the sea icethermodynamics could reduce these discrepancies with the data. Key Points - A grounding scheme is not enough to simulate landfast ice in Pan-Arctic simulations; - Both uniaxial and isotropic tensile strengths notably improve the simulation of landfast ice in deep coastal regions; - Simulated landfast ice season in the Kara Sea is still too short suggesting that thermodynamics should be improved